The coronavirus is not only claiming hundreds of thousands of lives, but is also causing a global economic crisis that is expected to rival or exceed that of any recession in the past 150 years. Although decisive action and containment measures are helping flatten the curve of infection, such measures inevitably deepen and lengthen the economic recession.In the worst-case scenario, the International Labour Organization (ILO) estimates that up to 25 million people will lose their jobs worldwide.Poverty, lack of social or economic opportunity and limited labour protections are the main root causes and drivers that render people vulnerable or cause them to fall victim to human trafficking. This unprecedented crisis will likely exacerbate all of those factors and result in developments that must be noted by antihuman-trafficking communities and stakeholders.