The links between technology and anti-trafficking—the focus of this Special Issue of Anti-Trafficking Review—and COVID-19 may seem topically distant and their analytical connections not readily apparent. However, by situating COVID-19 as an analytical launch pad into the Special Issue, our aim is to spark creative interdisciplinary approaches in tracking how distinctive global phenomena constitutively overlap in moments of social and economic disruption. And, more pointedly, we hope to better understand how issues framed as exceptional give rise to solutions, including state and non-governmental solutions augmented by technology, which may further contribute to structural vulnerabilities.